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| Product Name: | Fmoc-L-Lys(Boc)-OH | CAS No: | 71989-26-9 |
|---|---|---|---|
| M.W: | 468.54 | MF: | C26H32N2O6 |
| Appearance: | White Powder | Purity: | 98+ |
| EINECS No: | 276-256-4 | Storage: | 5-25°C |
Product Description
White Powder Fmoc-L-Lys(Boc)-OH CAS NO. 71989-26-9 Purity 98+
Name: Fmoc-L-Lys(Boc)-OH
CAS NO: 71989-26-9
M.W: 468.54
Appearance: White Powder
Purity: 98+
Synonyms: Nα-FMoc-Nε-Boc-L-lysine
Application
Polypeptide synthesis: As a lysine derivative, Fmoc-L-Lys(Boc)-OH plays an important role in polypeptide synthesis. Polypeptide synthesis refers to the process of connecting amino acids in a specific order to form polypeptide chains through a series of chemical reactions. In polypeptide synthesis, lysine is a common amino acid with two chiral carbon atoms, which requires special protection methods. Therefore, Fmoc-L-Lys(Boc)-OH can serve as an important intermediate for synthesizing polypeptides, providing special protection and connection methods for lysine.
Synthesis of antibody-drug conjugates (ADCs): Fmoc-L-Lys(Boc)-OH can be used as a cleavable ADC linker in the synthesis of antibody-drug conjugates (ADCs). ADCs are compounds that conjugate drugs to antibodies to accurately deliver the drugs to target cells or tissues. In the synthesis of ADCs, Fmoc-L-Lys(Boc)-OH can be connected to the antibody and drug through certain chemical reactions. Once the ADC reaches the target cells or tissues, the linker can be cleaved to release the drug, thereby achieving the therapeutic purpose.
Synthesis of PROTACs: Fmoc-L-Lys(Boc)-OH can be used as a PROTAC linker based on alkyl chain in the synthesis of PROTACs. PROTACs are molecules that degrade specific proteins using the ubiquitin-proteasome system, consisting of three parts: target protein ligand, linker, and E3 ubiquitin ligase ligand. In the synthesis of PROTACs, Fmoc-L-Lys(Boc)-OH can be connected to the target protein ligand and E3 ubiquitin ligase ligand through a series of chemical reactions to form the complete PROTAC molecule.
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