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Product Name: | Fmoc-Lys(Boc)-Osu | CAS No: | 132307-50-7 |
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M.W: | 565.61 | MF: | C30H35N3O8 |
Appearance: | White Powder | Purity: | 98+ |
EINECS No: | - | Storage: | 5-25°C |
Product Description
White Powder Fmoc-Lys(Boc)-Osu CAS NO. 132307-50-7 Purity 98+
Name: Fmoc-L-Lys(Palmitopyl)-OH
CAS NO: 132307-50-7
M.W: 565.61
Appearance: White Powder
Purity: 98+
Synonyms: N-ALPHA-FMOC-N-EPSILON-T-BOC-L-LYSINE N-HYDROXYSUCCINIMIDE ESTER; N-ALPHA-FMOC-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE N-HYDROXYSUCCINIMIDE ESTER
Application
In peptide synthesis, Fmoc-L-Lys(Palmitoyl)-OH serves as a surrogate for the natural L-Lys amino acid. It is commonly used in solid-phase peptide synthesis (SPPS) where the Fmoc group provides protection for the amino functionality during the synthetic process. The Palmitoyl moiety adds membrane affinity and lipophilicity to the peptide, which can be beneficial for certain applications such as membrane protein synthesis or the design of amphipathic peptides.
In protein engineering, Fmoc-L-Lys(Palmitoyl)-OH can be used to introduce palmitoylation sites into proteins. Palmitoylation is a post-translational modification that anchors proteins to cell membranes, affecting protein trafficking, localization, and function. By using this amino acid derivative, researchers can investigate the role of palmitoylation in protein function and design proteins with modified membrane-binding properties.
Drug development is another area where Fmoc-L-Lys(Palmitoyl)-OH can be beneficial. The compound can serve as a linker or chelator for the attachment of drugs or imaging agents to peptides or proteins. The palmitoyl group can also be used to target drugs to specific cells or tissues that express receptors for palmitate. This targeting ability can improve the pharmacokinetics and tissue distribution of drugs, leading to more effective treatment options.
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