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| Product Name: | Fmoc-Gly-Gly-Phe-OtBu-OH | CAS No: | 236426-37-2 |
|---|---|---|---|
| M.W: | 557.64 | MF: | C32H35N3O6 |
| Appearance: | White Powder | HPLC: | 98+ |
Product Description
Peptide Intermediate Fmoc-Gly-Gly-Phe-OtBu-OH CAS NO. 236426-37-2 HPLC 98+
Name: Fmoc-Gly-Gly-Phe-OtBu-OH
CAS NO: 236426-37-2
M.W: 557.64
Appearance: White Powder
Purity: 98+
Synonyms: Fmoc-Gly-Gly-Phe-OtBu
Application
Peptide Synthesis Process
Initiation: The synthesis typically starts with attaching the Fmoc-protected amino acid sequence (in this case, Fmoc-Gly-Gly-Phe-OtBu) to a solid support (resin) via its carboxylic acid group. This is known as the C-terminal (or carboxy-terminal) attachment.
Sequential Coupling: The Fmoc group is removed, exposing the amino group. This amino group is then coupled with the next Fmoc-protected amino acid in the desired sequence. This process is repeated until the entire peptide sequence is assembled.
Deprotection and Cleavage: After completing the sequence, the OtBu protecting group on the C-terminal amino acid is removed to reveal the free carboxylic acid. Then, the peptide is cleaved from the resin using a suitable reagent (e.g., trifluoroacetic acid, TFA).
Purification: The crude peptide is purified using techniques such as high-performance liquid chromatography (HPLC) to obtain the desired purity and homogeneity.
Potential Applications
The specific peptide synthesized using Fmoc-Gly-Gly-Phe-OtBu-OH as a starting point or intermediate will depend on the subsequent amino acids added and the intended application. These peptides can have a wide range of applications, including but not limited to:
Drug Development: As potential therapeutic agents or targets for drug discovery.
Biological Research: As probes for studying protein-protein interactions, enzyme substrates, or receptor ligands.
Diagnostic Tools: As biomarkers or components of diagnostic assays.
Package
Transportation
Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.
All transportation is in accordance with the customer's needs.
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