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Product Name: | Fmoc-D-Trp(Boc)-OH | CAS No: | 163619-04-3 |
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M.W: | 526.58 | MF: | C31H30N2O6 |
Appearance: | White Powder | Purity: | 98+ |
EINECS No: | - | Storage: | 5-25°C |
Product Description
White Powder Fmoc-D-Trp(Boc)-OH CAS NO. 143824-78-6 Purity 98+
Name: Fmoc-D-Trp(Boc)-OH
CAS NO: 163619-04-3
M.W: 526.58
Appearance: White Powder
Purity: 98+
Synonyms: FMOC-TRYPTOPHAN(BOC)-OH; FMOC-NIN-T-BUTYLOXYCARBONYL-D-TRYPTOPHAN
Application
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that is used in the synthesis of antibody-drug conjugates (ADCs). ADCs consist of three components: an antibody that recognizes tumor cell surface antigens, an ADC cytotoxin that exerts a cytotoxic effect, and an ADC linker that attaches the cytotoxin to the antibody.
Specifically, this cleavable ADC linker can be activated in the intracellular environment, releasing the cytotoxin and killing tumor cells. This drug design can reduce toxicity to normal cells and improve the specificity and effectiveness of treatment.
Package
Transportation
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