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Product Name: | Boc-L-Hyp-OH | CAS No: | 13726-69-7 |
---|---|---|---|
M.W: | 231.25 | MF: | C10H17NO5 |
Appearance: | White Powder | Purity: | 98+ |
EINECS No: | 604-011-7 | Storage: | 5-25°C |
Highlight: | C10H17NO5 BOC-Amino Acids,Boc-L-Hyp-OH,CAS NO. 13726-69-7 |
Product Description
White Powder Boc-L-Hyp-OH CAS NO. 13726-69-7 Purity 98+
Name: Boc-L-Hyp-OH
CAS NO: 13726-69-7
M.W: 231.25
Appearance: White Powder
Purity: 98+
Synonyms: (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
Application
Boc-L-Hyp-OH is a chemical substance with the molecular formula C7H15NO5. It is a non-cleavable ADC linker that is primarily used in the synthesis of antibody-drug conjugates (ADCs). Additionally, Boc-L-Hyp-OH is an alkyl chain-based PROTAC linker that can be employed in the synthesis of PROTACs.
In the context of ADC synthesis, antibodies are conjugated to cell toxins through the ADC linker, forming the drug conjugate. PROTACs, on the other hand, consist of two distinct ligands: one targeting E3 ubiquitin ligases and the other targeting the target protein. PROTACs utilize the cellular ubiquitin-proteasome system to selectively degrade target proteins.
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