Semaglutide Intermediate Boc-His(trt)-Gly CAS 1428125-85-2 HPLC 99+

Product Description

Semaglutide Intermediate Boc-His(trt)-Gly CAS 1428125-85-2 HPLC 99+

Name: Boc-His(trt)-Gly

CAS NO: 1428125-85-2

M.W: 554.64

Appearance: White Powder

Purity: 98+

Synonyms:  2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(1-tritylimidazol-4-yl)propanoyl]amino]acetic acid

Application

Peptide Synthesis: Boc-His(trt)-Gly serves as a building block in peptide synthesis, where it can be sequentially assembled with other amino acid derivatives using solid-phase peptide synthesis (SPPS) or liquid-phase peptide synthesis (LPS) techniques to form peptides with specific sequences and structures.

Protection of Side Chain Functional Groups: During the synthesis of peptides containing histidine, the imidazole side chain of histidine can participate in unwanted side reactions. The use of His(trt)-protected histidine, such as Boc-His(trt)-Gly, allows the sensitive side chain functional group to be protected during synthesis and only removed later.

Enhancing Peptide Stability: Appropriate protection strategies, such as the use of Boc and trt protecting groups, can enhance the stability of peptides during synthesis and subsequent experiments. This helps maintain the biological activity and structural integrity of the peptides.

Biochemical Research: Boc-His(trt)-Gly and its related peptide derivatives can be used in biochemical research to explore the role of histidine in protein function, enzymatic activity, and cell signaling pathways. These studies aid in understanding the biological mechanisms of peptides and proteins within living systems.

Drug Design and Development: In drug design and development, peptides and peptidomimetics are often explored as potential therapeutic candidates. Boc-His(trt)-Gly and similar derivatives can be used to synthesize peptide analogs with specific biological activities, which may possess novel therapeutic potential or optimized pharmacokinetic properties.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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