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Home ProductsFMOC-Amino Acids

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production
Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production

Large Image :  Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production Get Best Price

Product Details:
Place of Origin: CHINA
Brand Name: Enlai Biotech
Certification: ISO 9001 COA HPLC NMR
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Inside: double PE bag Outside: paper drum
Delivery Time: In Stock
Payment Terms: T/T
Supply Ability: 100 kilograms per month
Detailed Product Description
Product Name: Fmoc-Arg(pbf)-OH CAS No: 154445-77-9
M.W: 648.77 Isomer: 0
Appearance: White Powder HPLC: 99+

 

Product Description

 

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production

 

NameFmoc-Arg(pbf)-OH

CAS NO: 154445-77-9

M.W648.77

Appearance: White Powder

Purity: 98+  

Synonyms: Fmoc-pbf-L-Arginine

 

Application

 

To synthesize semaglutide using Fmoc-Arg(pbf) as one of the components, the general steps involve:

 

Initially, the Fmoc-protected dipeptide fragment Fmoc-Arg(Pbf)-Gly-OH is coupled to a solid-phase resin carrier, resulting in Fmoc-Arg(Pbf)-Gly-resin. The solid-phase carrier can be polystyrene-based resins such as Wang resin, CTC resin, or PHB resin.

 

Subsequently, N-terminal Fmoc-protected and side chain-protected amino acids as well as dipeptide fragments are sequentially coupled in accordance with the peptide sequence of semaglutide. This step involves chemically linking amino acids in a specific order to form the peptide chain of semaglutide.

 

Once the peptide chain synthesis is complete, the peptide resin is cleaved to obtain the peptide backbone. This step removes the resin carrier and transfers the peptide from the solid phase to the liquid phase.

 

Next, the side chain is attached to the ε-NH of the lysine residue at position 20, and the protective groups are removed. This step completes the side chain modification and deprotection of semaglutide, enabling its biological activity.

 

Finally, semaglutide is purified to obtain the final product. Purification steps may include filtration, crystallization, chromatography separation, and other methods to remove impurities and improve the purity and quality of the product.

 

Package

 

 Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 0     Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 1 

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 2Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 3

Transportation

 

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

 

Company Profile

 

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 4Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 5

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 6Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 7

Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 8Semaglutide intermediate Fmoc-Arg(pbf)-OH CAS 154445-77-9 Bulk Production 9

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