Semaglutide intermediate Fmoc-Glu(OtBu)-OH CAS 71989-18-9 HPLC 99.5+

Product Description

Semaglutide intermediate Fmoc-Glu(OtBu)-OH CAS 71989-18-9 HPLC 99.5+

Name: Fmoc-Glu(OtBu)-OH

CAS NO: 71989-18-9

M.W: 425.47

Appearance: White Powder

Purity: 98+

Synonyms: Fmoc-L-Glutamic Acid 5-tert-butyl ester

Application

The Role of Fmoc-Glu(OtBu)-OH in the Synthesis of Semaglutide

Fmoc-Glu(OtBu)-OH (N-Fmoc-L-glutamic acid γ-t-butyl ester) does not directly serve as a part of Semaglutide in its final chemical structure. However, it may be used as an intermediate or linker in the synthesis of complex peptide sequences, including those related to Semaglutide.

Fmoc-Glu(OtBu)-OH possesses specific chemical properties such as melting point, relative density, and it can be used as a ligand, a linker in the preparation of small molecule conjugates, and in the preparation of peptide C-terminal thioesters. These properties make it a useful compound in the field of peptide synthesis.

However, the synthesis of Semaglutide is a complex process involving the connection and modification of multiple amino acids. The specific amino acid sequence of Semaglutide does not directly correspond to Fmoc-Glu(OtBu)-OH. Semaglutide consists of 38 amino acid residues connected by peptide bonds, forming a helical structure with specific hydrogen bonds and disulfide bonds.

Therefore, while Fmoc-Glu(OtBu)-OH may have a role in peptide synthesis, it does not directly participate in the synthesis of Semaglutide. The synthesis of Semaglutide requires the use of specific starting materials, reagents, and conditions, with solid-phase peptide synthesis (SPPS) methods used to gradually build the desired amino acid sequence.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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