Nintedanib Intermediate Boc-Phe(4-NO2)-OH CAS NO. 67630-00-6 HPLC 99+

Product Description

Nintedanib Intermediate Boc-Phe(4-NO2)-OH CAS NO. 67630-00-6 HPLC 99+

Name: Boc-Phe(4-NO2)-OH

CAS NO: 67630-00-6

M.W: 338.36

Appearance: White Powder

Purity: 98+   

Synonyms: Boc-Phe(4-NO2)-OH

Application

As a Starting Material or Intermediate

Firstly, Boc-Phe(4-NO₂)-OH could serve as a starting material or an intermediate in the synthesis of Nintedanib. In complex organic syntheses, protected amino acids like Boc-Phe(4-NO₂)-OH are often used to introduce specific chemical functionalities that are later transformed into the desired product. The Boc (tert-butoxycarbonyl) group protects the amino functionality, allowing for selective reactions on other parts of the molecule.

Providing Unique Chemical Features

Secondly, the presence of the nitro (NO₂) group and the phenylalanine structure in Boc-Phe(4-NO₂)-OH may confer unique chemical properties that are essential for the biological activity or pharmacokinetics of Nintedanib. The nitro group can act as a versatile handle for further transformations, such as reduction to an amino group or displacement reactions. Meanwhile, the phenylalanine moiety is known to play important roles in protein-ligand interactions and may contribute to the specificity and potency of Nintedanib.

Linking to the Overall Synthesis Strategy

To fully appreciate the role of Boc-Phe(4-NO₂)-OH in the synthesis of Nintedanib, it is necessary to consider the overall synthesis strategy. This often involves multiple steps, each designed to transform the starting materials into intermediates that are increasingly similar to the final product. Boc-Phe(4-NO₂)-OH may be incorporated at an early stage, undergoing a series of transformations that eventually lead to its incorporation into the Nintedanib structure.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

Company Profile