Nintedanib Intermediate Phe(4-NO2)-OH CAS NO. 949-99-5 HPLC 99+

Product Description

Nintedanib Intermediate Phe(4-NO2)-OH CAS NO. 949-99-5 HPLC 99+

Name: Phe(4-NO2)-OH

CAS NO: 949-99-5

M.W: 210.19

Appearance: White Powder

Purity: 98+   

Synonyms: Phe(4-NO2)-OH

Application

As an Intermediate or Precursor

Phe(4-NO₂)-OH may be used as an intermediate or precursor in the synthesis, undergoing various chemical transformations to incorporate it into the complex structure of Nintedanib. These transformations could include protection/deprotection reactions, coupling reactions with other intermediates, or modifications of the nitro group, such as reduction to an amino group or displacement reactions.

Providing the Necessary Chemical Motifs

The phenylalanine moiety in Phe(4-NO₂)-OH provides a critical aromatic structure that may be required for the biological activity or interaction with target molecules of Nintedanib. Additionally, the nitro group offers a versatile handle for further chemical manipulations, allowing for the introduction of other functional groups or the formation of specific bonds that are essential for the final structure of the drug.

Linking to the Overall Synthesis Strategy

The role of Phe(4-NO₂)-OH in the synthesis of Nintedanib will ultimately depend on the specific synthetic route chosen. Different research groups may have developed different strategies, each with its own set of intermediates and reaction conditions. However, it is likely that Phe(4-NO₂)-OH, or a derivative of it, will be incorporated at some point during the synthesis to provide the necessary chemical motifs and reactivity for the formation of Nintedanib.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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