Tilpotide Intermediate Fmoc-Ser-OH CAS NO. 73724-45-5 HPLC 99+

Product Description

Tilpotide intermediate Fmoc-Ser-OH CAS NO. 73724-45-5 HPLC 99+

Name: Fmoc-Ser-OH

CAS NO: 73724-45-5

M.W: 327.33

Appearance: White Powder

HPLC: 99+

Synonyms: Fmoc-L-serine

Application

Protection Group:During polypeptide synthesis, Fmoc (9-fluorenylmethoxycarbonyl) is frequently employed as an N-terminal protecting group for amino acids to prevent undesirable side reactions during the reaction process. As an Fmoc-protected serine derivative, Fmoc-L-serine enables the introduction of serine residues through amidation reactions during the elongation of the polypeptide chain, while simultaneously protecting its N-terminus from interference.

Structural Modification:The reactive carboxyl and amide groups of Fmoc-L-serine allow it to undergo condensation reactions with alcohol or amine compounds, leading to the synthesis of desired ester or amide derivatives. This capability renders Fmoc-L-serine a crucial player in the structural modification of polypeptides, including polypeptide drugs like Tilpotide, which may require the introduction of specific modifying groups during synthesis to enhance their stability, biological activity, or pharmacokinetic properties.

Solid-Phase Peptide Synthesis (SPPS):In solid-phase peptide synthesis, Fmoc-protected amino acid derivatives such as Fmoc-L-serine are widely utilized. By sequentially attaching Fmoc-L-serine and other amino acids to a solid-phase support, polypeptides with specific sequences and structures can be efficiently synthesized. This method holds significant practical importance for the preparation of complex polypeptide drugs, like Tilpotide.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

Company Profile