Tilpotide Intermediate Fmoc-leu-OH CAS NO. 35661-60-0 HPLC 99+

Product Description

Tilpotide intermediate Fmoc-leu-OH CAS NO. 35661-60-0 HPLC 99+

Name: Fmoc-leu-OH

CAS NO: 35661-60-0

M.W: 353.41

Appearance: White Powder

HPLC: 9+

Synonyms: FMOC-L-LEUCINE

Application

N-Terminal Protection:Fmoc (9-fluorenylmethoxycarbonyl), being an alkaline-sensitive protecting group, is routinely employed in polypeptide synthesis to safeguard the N-terminus of amino acids. Fmoc-L-leucine, as the Fmoc-protected derivative of L-leucine, effectively prevents unwanted reactions at the amino group of L-leucine during the synthesis process, ensuring precision and efficiency in the synthetic steps.

Efficient Incorporation of Amino Acid Residues:Due to its stability and reactivity, Fmoc-L-leucine enables the efficient introduction of L-leucine residues through amidation reactions during the elongation of the polypeptide chain. This characteristic contributes to accelerating the synthesis rate of polypeptides and enhancing the purity of the final product.

Potential for Structural Modification:The reactive carboxyl and amide groups of Fmoc-L-leucine allow it to undergo condensation reactions with alcohols or amines, facilitating the synthesis of desired ester or amide derivatives. This capability赋予Fmoc-L-leucine significant value in the structural modification of polypeptides, making it a crucial intermediate or starting material for enhancing the properties of polypeptides such as Tilpotide.

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