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Product Name: | Fmoc-Asn(Trt)-OH | CAS No: | 132388-59-1 |
---|---|---|---|
MF: | C38H32N2O5 | Appearance: | White Powder |
HPLC: | 99+ | Storage: | 5-25°C |
Highlight: | Atosiban Intermediate Fmoc-Asn(Trt)-OH,HPLC Fmoc-Asn(Trt)-OH,CAS NO. 132388-59-1 Fmoc-Asn(Trt)-OH |
Product Description
Atosiban Intermediate Fmoc-Asn(Trt)-OH CAS NO. 132388-59-1 HPLC 99+
Name: Fmoc-Asn(Trt)-OH
CAS NO: 132388-59-1
M.W: 596.67
Appearance: White Powder
HPLC: 99+
Synonyms: N-ALPHA-FMOC-N-GAMMA-TRITYL-L-ASPARAGINE; FMOC-ASPARAGINE(TRT)
Application
Synthesis Strategy Component:In the synthesis process of polypeptide drugs such as Atosiban, N-Fmoc-N'-trityl-L-aspartic acid may serve as a vital part of the synthesis strategy, contributing to the construction of complex polypeptide structures. The Fmoc (fluorenylmethoxycarbonyl) group is frequently employed for the protection of α-amino groups during polypeptide synthesis, while the trityl (Trt) group may function as a protective or modifying moiety for γ-carboxyl groups, aiding in the control of reaction pathways and enhancing selectivity.
Application of Protective Groups:Within the synthetic pathway of Atosiban or its analogs, N-Fmoc-N'-trityl-L-aspartic acid may act as a temporary protective group, safeguarding specific functional groups of amino acids from unintended reactions during synthesis. In the later stages of synthesis, these protective groups can be removed through appropriate chemical methods, restoring the original functional group activity.
Purity Enhancement and Quality Control:As a high-purity reagent, N-Fmoc-N'-trityl-L-aspartic acid can be utilized in the preparation of intermediates for Atosiban, thereby enhancing the purity and quality of the final product. In the synthesis of polypeptide drugs, the purity of each raw material at every step is paramount, as it directly impacts the efficacy and safety of the end product.
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