Atosiban Intermediate Fmoc-Pro-OH CAS NO. 71989-31-6 HPLC 99+

Product Description

Atosiban Intermediate Fmoc-Pro-OH CAS NO. 71989-31-6 HPLC 99+

Name: Fmoc-Pro-OH

CAS NO: 71989-31-6

M.W: 337.37

Appearance: White Powder

HPLC: 99+  

Synonyms: N-9-FLUORENYLMETHYLOXYCARBONYL-L-PROLINE; N-(9-FLUOROENYLMETHOXYCARBONYL)-L-SERINE

Application

As a Synthetic Intermediate:Fmoc-L-proline may serve as a crucial intermediate in the synthesis pathway of Atosiban. In solid-phase peptide synthesis, the Fmoc group is frequently utilized to protect the α-amino group of amino acids, preventing unwanted side reactions during coupling reactions. Consequently, Fmoc-L-proline may be incorporated into the peptide chain of Atosiban to construct the specific amino acid sequence.

Enhancing Synthesis Efficiency and Purity:Using Fmoc-L-proline as a synthetic intermediate aids in controlling reaction conditions, thereby improving synthesis efficiency. Additionally, since the Fmoc group can be readily removed under specific conditions, this facilitates the restoration of the amino acid's original functional group activity in the later stages of synthesis, ultimately enhancing the purity and quality of the final product.

Promoting Selective Reactions:Selectivity is paramount in peptide synthesis. The presence of the Fmoc group assists in controlling reaction pathways, fostering the coupling of specific amino acids, and minimizing the formation of byproducts. This is particularly crucial for the synthesis of complex, highly active polypeptide drugs such as Atosiban.

Participation in Specific Synthetic Strategies:Certain synthetic strategies may rely on the unique properties of Fmoc-L-proline. For instance, when employing the Fmoc solid-phase peptide synthesis method to synthesize Atosiban, Fmoc-L-proline may act as one of the protected amino acid segments, sequentially incorporated into the peptide chain according to a precise peptide-linking sequence.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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