Tirzepatide Intermediate Boc-Ala-Gly-OH CAS NO. 28782-78-7

Product Description

Tirzepatide Intermediate Boc-Ala-Gly-OH CAS NO. 28782-78-7

Name: Boc-Ala-Gly-OH

CAS NO: 28782-78-7

M.W: 246.26

Appearance: White Powder

Purity: 99+   

Synonyms: BOC-ALA-GLY-OH

Application

1. As a Synthetic Intermediate

During the process of peptide synthesis, BOC-ALA-GLY-OH can serve as an intermediate for synthesizing specific peptides. By introducing this fragment, the synthesis steps can be simplified, and the synthesis efficiency can be improved. For example, when synthesizing certain peptides with specific biological activities, BOC-ALA-GLY-OH can be first connected with other amino acid fragments to form a longer peptide chain, which can then be further modified and functionalized.

2. Role of the Protecting Group

BOC (tert-butyloxycarbonyl), as a commonly used amino protecting group, plays a pivotal role in peptide synthesis. It protects the amino group of amino acids from unnecessary reactions, ensuring the smooth progress of the synthesis process. In BOC-ALA-GLY-OH, the BOC group protects the amino group of alanine, allowing this fragment to undergo coupling reactions with other amino acid fragments under relatively mild conditions.

3. Participation in Solid-Phase Peptide Synthesis

Solid-phase peptide synthesis is a commonly used method for peptide synthesis, utilizing a solid-phase support to sequentially link amino acids into a peptide chain. BOC-ALA-GLY-OH can serve as a fragment in solid-phase synthesis, covalently bonded to the solid-phase support and serving as the starting point for subsequent peptide chain elongation. In solid-phase synthesis, the removal of the BOC group is typically achieved using reagents such as trifluoroacetic acid (TFA), and the BOC group in BOC-ALA-GLY-OH follows this removal mechanism.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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