Boc-Trp(1-Me)-OH CAS NO. 109927-44-8 HPLC 99+

Product Description

Boc-Trp(1-Me)-OH CAS NO. 109927-44-8 HPLC 99+

Name: Boc-Trp(1-Me)-OH

CAS NO: 109927-44-8

M.W: 318.37

Appearance: White Powder

HPLC: 99+

Synonyms: Boc-Trp(Me)-OH

Application

Protecting Group Function: The Boc group protects the α-amino group during synthesis, preventing unwanted side reactions. It can be easily removed under acidic conditions (e.g., using trifluoroacetic acid, TFA) to allow peptide chain elongation.
The methylation on the indole side chain protects it from side reactions and adds unique chemical properties to the peptide.

Peptide Design:Peptides incorporating methylated tryptophan often exhibit enhanced stability and resistance to enzymatic degradation.The methylated indole group can modify molecular interactions such as hydrogen bonding, hydrophobic interactions, and π-π stacking, which significantly influence peptide folding and functionality.

Mimicking Protein Methylation: In natural proteins, tryptophan methylation is an important post-translational modification (PTM) that regulates cell signaling, protein-protein interactions, and gene expression. Boc-Trp(Me)-OH is used to: Mimic Methylated Residues in Proteins: By incorporating Boc-Trp(Me)-OH into peptides, researchers can simulate methylated residues in natural proteins and study their functional implications.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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