Di-peptide 71952-99-3 Fmoc-Gly-Ala-OH HPLC 99+

Product Description

Di-peptide 71952-99-3 Fmoc-Gly-Ala-OH HPLC 99+

Name: Fmoc-Gly-Ala-OH

CAS NO: 71952-99-3

M.W: 368.39

Appearance: White Powder

HPLC: 99+  

Synonyms: Fmoc-Gly-Ala-OH

Application

Solid-Phase Peptide Synthesis (SPPS)

Fmoc-Gly-Ala-OH serves as a pre-synthesized dipeptide unit, reducing the number of coupling steps in Fmoc-based SPPS and improving efficiency.

Reduces the risk of racemization during sequential synthesis, especially when coupled to amino acids prone to epimerization (e.g., Cys, His, Ser).

Enhances synthesis efficiency compared to stepwise single amino acid coupling.

2. Structural Role in Peptides

The Gly-Ala dipeptide motif is common in natural proteins and peptides, contributing to specific secondary structures like β-sheets and α-helices.

Glycine (Gly) provides flexibility, while Alanine (Ala) with a methyl side chain affects peptide folding and structural conformation.

3. Pharmaceutical & Bioactive Peptide Applications

Used in bioactive peptide synthesis, such as antimicrobial peptides (AMPs), cell-penetrating peptides (CPPs), and enzyme-inhibiting peptides.

Applied in PROTACs, bifunctional molecules, or modified peptides to enhance metabolic stability and bioactivity.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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