Fmoc Protected Fmoc-α-Me-Tyr(tBu)-OH CAS No 1309873-74-2 HPLC 99+

Product Description

Fmoc Protected Fmoc-α-Me-Tyr(tBu)-OH CAS No 1309873-74-2 HPLC 99+

Name: Fmoc-α-Me-Tyr(tBu)-OH

CAS NO: 1309873-74-2

M.W: 473.56

Appearance: White Powder

HPLC: 99+  

Synonyms: Fmoc-α-Me-Tyr(tBu)-OH

Application

1. Conformational Restriction

The α-methylation restricts backbone rotation, making the peptide more rigid.

This can stabilize secondary structures, such as α-helices or β-turns, especially in bioactive peptides.

2. Protease Resistance

The α-methyl group protects against enzymatic degradation, increasing peptide stability in biological systems.

Ideal for designing stable therapeutic peptides.

3. Peptidomimetics and Drug Design

Used in protein–protein interaction (PPI) inhibitors, where rigidity and metabolic stability are critical.

Often applied in cancer, inflammation, and infectious disease research.

4. Hydrophobic and Aromatic Interaction Enhancement

Tyrosine contributes aromatic π–π stacking and hydrophobic interactions, while α-methylation enhances lipophilicity.

Useful for target binding affinity improvement.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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