Peptide Impurity Boc-His(Trt)-His(Trt)-OH HPLC 98+

Product Description

Peptide Impurity Boc-His(Trt)-His(Trt)-OH HPLC 98+

Name: Boc-His(Trt)-His(Trt)-OH

CAS NO: NA

M.W: 879.0

Appearance: White Powder

Purity: 98+   

Synonyms: Boc-Phe-NH2

Application

1. Used in Solid-Phase Peptide Synthesis (SPPS)

Boc protects the N-terminal amine, while Trt protects the imidazole side chains of the two histidine residues.

This dipeptide is often used as a building block in the stepwise synthesis of longer peptides, improving efficiency and reducing the number of coupling steps.

2. Application in Drug Development

Histidine residues play important roles in bioactive peptides, especially those involving metal coordination or enzymatic activity.

His-His motifs are frequently incorporated into targeted peptide drugs or enzyme inhibitors to improve binding affinity to biological targets.

3. For Studying His-Containing Functional Peptides

The His-His sequence is critical in regulating metal-protein interactions, such as binding to Zn²⁺ or Ni²⁺.

This dipeptide can be used to model or study metal coordination behavior and molecular recognition processes in biochemical research.

4. Building Block for Peptide Libraries

In combinatorial peptide library construction, incorporating a His-His motif introduces diversity and potential biological functionality.

Useful in screening for peptides with specific bioactivity or binding profiles.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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