Di-peptide Impurity Fmoc-Thr(tBu)-Ser-OH HPLC 98+ CAS 2171282-46-3

Product Description

Di-peptide Impurity Fmoc-Thr(tBu)-Ser-OH HPLC 98+ CAS 2171282-46-3

Name: Fmoc-Thr(tBu)-Ser-OH

CAS NO: 2171282-46-3

M.W: 484.5

Appearance: White Powder

HPLC: 98+  

Synonyms: Fmoc-Thr(tBu)-Ser-OH

Application

1. Solid-Phase Peptide Synthesis (SPPS)

Fmoc-Thr(tBu)-Ser-OH is a protected dipeptide building block, commonly used in SPPS to efficiently construct peptides that contain a Thr-Ser sequence.

The Fmoc group protects the N-terminal amine, and the tBu group protects the hydroxyl side chain of threonine during synthesis.

Preassembled dipeptides like this help reduce synthesis time, improve coupling efficiency, and minimize side reactions.

2. Synthesis of Bioactive Peptides

The Thr-Ser motif is frequently found in natural peptides and proteins, especially:

Phosphorylation sites (commonly in signaling pathways),

O-linked glycosylation sites (especially in mucins and membrane-bound proteins).

Therefore, this dipeptide is useful for synthesizing peptides used in biomedical research, such as signal peptides, glycopeptides, or therapeutic analogs.

3. Combinatorial Peptide Libraries

Used in the creation of peptide libraries for drug discovery, protein binding studies, or enzyme substrate profiling.

Thr-Ser sequences can modulate hydrophilicity, flexibility, and interaction with biological targets.

4. Custom Peptide Design with Controlled Structure

When precise control over hydrogen bonding and secondary structure is desired (e.g., β-turns or loops), this dipeptide is helpful.

It ensures accurate incorporation of hydroxyl-containing residues, which are critical for intermolecular interactions.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

Company Profile