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Product Name: | Fmoc-L-Lys(PaGlu-Otbu)-OH | CAS No: | 1491158-62-3 |
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M.W: | 792.06 | MF: | C46H69N3O8 |
Appearance: | White Powder | Purity: | 98+ |
EINECS No: | - | Storage: | 5-25°C |
Product Description
White Powder Fmoc-L-Lys(PaGlu-Otbu)-OH CAS NO.1491158-62-3 Purity 98+
Name:Fmoc-L-Lys(PaGlu-Otbu)-OH
CAS NO: 1491158-62-3
M.W:792.06
Appearance: White Powder
Purity: 98+
Synonyms: Fmoc-Lys(Pal-Glu-OtBu)-OH;N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(N-alpha'-palmitoyl-L-glutamic-acidalpha'-t-butylester)-L-lysine;Fmoc-L-Lys(Palm-L-Glu-OtBu)-OH;
Application
Antibody-drug conjugates (ADCs): This compound is a degradable ADC linker that is used in the synthesis of antibody-drug conjugates (ADCs). ADCs are a type of targeted therapy that combines the specificity of antibodies with the potency of cytotoxic agents to treat cancer and other diseases. By using Fmoc-L-Lys(Pal-Glu-OtBu)-OH as a linker, it allows for the conjugation of cytotoxic agents to antibodies, resulting in ADCs with improved therapeutic efficacy and reduced side effects.
PROTACs: PROTACs are protein degradation agents that utilize a bivalent ligand to recruit E3 ligases to specific proteins, leading to their degradation. Fmoc-L-Lys(Pal-Glu-OtBu)-OH can serve as a PROTAC linker based on its alkyl chain, connecting the protein binding moiety and the E3 ligase recruiting moiety. This linker plays a crucial role in PROTAC design and can help to develop new drugs that target proteins for degradation.
Package
Transportation
Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.
All transportation is in accordance with the customer's needs.
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