Peptide Synthesis Fmoc-MeTrp-OH CAS 112913-63-0 Purity 98+

Product Description

Peptide Synthesis Fmoc-MeTrp-OH CAS 112913-63-0 Purity 98+

Name: Fmoc-N-Me-Trp-OH

CAS NO: 112913-63-0

M.W: 440.49

Appearance: White Powder

Purity: 98+   

Synonyms: Fmoc-Trp(me)-OH; Fmoc-N-Methyl-Tryptophan

Application

As a Building Block: In the process of peptide synthesis, Fmoc-MeTrp serves as a crucial building block that can be connected to other amino acids through peptide bonds, forming polypeptide chains with specific sequences and functions. The specific sequence and function are crucial for the biological activity of the polypeptide.

Providing Methylation Modification: Since Fmoc-MeTrp contains a methyl (-CH₃) group on the side chain of tryptophan, it can provide methylation modification to the polypeptide. Methylation is a common biological modification that can alter the biological activity and interaction patterns of molecules. Therefore, the introduction of Fmoc-MeTrp may change certain biological properties of the polypeptide, such as its ability to bind to specific receptors or its enzymatic stability.

Protecting and Stabilizing the Peptide Chain: In solid-phase peptide synthesis, the Fmoc group serves as a protective group that safeguards the α-amino group of the amino acid from unwanted reactions. This protection ensures the stability and correct assembly of the peptide chain during synthesis. Once synthesis is complete, the Fmoc group can be removed under appropriate chemical conditions, releasing the free amino group.

Influencing Peptide Conformation and Biological Activity: The introduction of Fmoc-MeTrp may alter the conformation and biological activity of the polypeptide. Tryptophan is an amino acid with an aromatic ring and side chain, and its inclusion may increase the hydrophobicity or change the spatial conformation of the polypeptide, thereby affecting its interaction with target molecules and biological activity.

Research and Development of New Drugs: Due to its unique structure and biological activity, Fmoc-MeTrp may be used in the research and development of new drugs. By introducing this unnatural amino acid, it is possible to mimic or alter the structure and function of natural peptides and proteins, leading to the discovery of drug candidates with novel mechanisms of action.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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