Tilpotide intermediate Fmoc-Pro-Pro-OH CAS 129223-22-9 HPLC 99+

Product Description

Tilpotide intermediate Fmoc-Pro-Pro-OH CAS 129223-22-9 HPLC 99+

Name:Fmoc-L-Pro-Pro-OH

CAS NO: 129223-22-9

M.W:434.48

Appearance: White Powder

Purity: 98+   

Synonyms: Fmoc-Prolinyl-Proline

Application

Starting Materials and Protective Groups: First, Fmoc-Pro-Pro-OH could be used as one of the starting materials, or its protected amino acid fragment may be incorporated into the synthesis of a specific part of tirzepatide. In solid-phase peptide synthesis (SPPS), the amino and carboxyl groups of amino acids are typically protected to prevent unwanted reactions during the synthesis process.

Peptide Chain Assembly: In SPPS, starting materials like Fmoc-Pro-Pro-OH (or its protected fragments) are sequentially coupled onto a solid-phase support (e.g., resin). Through repeated cycles of washing, deprotection, and coupling steps, the complete peptide chain is gradually built up.

Side Chain Modifications: In the synthesis of tirzepatide, some amino acids may have specific side chains. If Fmoc-Pro-Pro-OH or its derivatives are used as side chain precursors, they would need to be attached to the appropriate amino acid residues under suitable reaction conditions to form the complete peptide chain.

Resin Cleavage and Purification: Once the peptide chain is synthesized, it is cleaved from the solid-phase support using specific chemical treatments (e.g., trifluoroacetic acid). The crude peptide is then purified and characterized using techniques such as chromatography and mass spectrometry to ensure its quality and purity.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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