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Product Name: | Tyr(tbu)-OH | CAS No: | 18822-59-8 |
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MF: | C13H19NO3 | Appearance: | White Powder |
HPLC: | 99+ | Storage: | 5-25°C |
Highlight: | Tyr(tbu)-OH CAS NO. 18822-59-8,HPCL 99+ Tyr(tbu)-OH,Tilpotide Tyr(tbu)-OH |
Product Description
Tilpotide intermediate Tyr(tbu)-OH CAS NO. 18822-59-8 HPCL 99+
Name: Tyr(tbu)-OH
CAS NO: 18822-59-8
M.W: 237.29
Appearance: White Powder
HPLC: 99+
Synonyms: O-tert-Butyl-L-tyrosine
Application
As a Synthetic Raw Material or Intermediate:In the synthesis process of polypeptide drugs, O-tert-butyl-L-tyrosine can serve as one of the raw materials or intermediates for the synthesis of Tilpotide (or similar polypeptides). Scientists can introduce O-tert-butyl-L-tyrosine at appropriate positions within the target sequence of Tilpotide to construct a polypeptide chain with specific biological activities.Due to the presence of the tert-butyl protecting group, O-tert-butyl-L-tyrosine can protect the phenolic hydroxyl group from unnecessary reactions during synthesis, thereby enhancing synthesis efficiency and product purity.
Structural Modification and Functional Enhancement:The incorporation of O-tert-butyl-L-tyrosine may alter the physicochemical properties and biological activities of Tilpotide (or similar polypeptides). For instance, the tert-butyl protecting group can increase the hydrophobicity and stability of the polypeptide, thereby influencing its pharmacokinetic properties and bioavailability.Furthermore, O-tert-butyl-L-tyrosine may interact with other amino acids or molecules, affecting the overall structure and function of Tilpotide, potentially enhancing its therapeutic effects or reducing side effects.
Drug Design and Optimization:During the drug design process, scientists can utilize O-tert-butyl-L-tyrosine as a tool molecule to modify and optimize the structure of Tilpotide (or similar polypeptides). By altering parameters such as the type, position, and number of protecting groups, they can explore the impact of different structures on the biological activity of the polypeptide, ultimately screening for drug candidates with superior performance.
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