Tirzepatide Intermediate Boc-Gly-Pro-OH CAS 14296-92-5

Product Description

Tirzepatide Intermediate Boc-Gly-Pro-OH CAS NO. 14296-92-5

Name: Boc-Gly-Pro-OH

CAS NO: 14296-92-5

M.W: 272.3

Appearance: White Powder

HPLC: 99+   

Synonyms: BOC-GLY-PRO-OH

Application

Introduction of a Specific Sequence: Boc-Gly-Pro-OH is a pre-synthesized tripeptide that contains glycine and proline, which can be directly incorporated into a peptide chain to introduce this specific sequence. Proline, in particular, plays a role in creating bends in peptide chains, so using Boc-Gly-Pro-OH can provide structural advantages.

Sequence Control: Adding a pre-formed Boc-Gly-Pro-OH fragment to the growing chain allows for more precise control over the amino acid sequence, which is particularly useful in complex or long peptide syntheses.

Pre-synthesized Fragment: As a tripeptide, Boc-Gly-Pro-OH reduces the need to add amino acids one-by-one, which can be time-consuming in long-chain peptides. Using this fragment can improve efficiency and streamline synthesis, especially for lengthy sequences.

Reduced Side Reactions: Since Boc-Gly-Pro-OH is a pre-synthesized and protected tripeptide, side reactions are minimized compared to individual amino acid coupling. After deprotecting the Boc group, it can directly couple with the carboxy or amino end of another peptide segment.

Solid-Phase Synthesis (SPPS): Boc-Gly-Pro-OH is commonly used in SPPS, where peptide chains are synthesized step-by-step on a solid resin. The Boc group can be removed in controlled acidic conditions to sequentially build the peptide.
Liquid-Phase Synthesis: Boc-Gly-Pro-OH can also be used in liquid-phase synthesis, where it acts as a solution-phase fragment that can couple with other segments in solution. Liquid-phase synthesis is often used for shorter or less complex peptides.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

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