Boc-N-Me-Leu-OH CAS 53363-89-6 Boc-N-Methyl-L-Leucine

Product Description

Boc-N-Me-Leu-OH CAS 53363-89-6 Boc-N-Methyl-L-Leucine

Name: Boc-N-Me-Leu-OH

CAS NO: 53363-89-6

M.W: 245.32

Appearance: White Powder

Purity: 98+   

Synonyms: Boc-N-Methyl-L-Leucine

Application

Peptide Drug Design:

Boc-N-Me-Leu-OH can be used in the synthesis of therapeutic peptides with improved stability, bioactivity, and resistance to enzymatic degradation. For example, N-methylleucine is often included in peptides designed to inhibit enzymes or bind to receptors in a highly specific way.
The Boc protective group ensures that the amine group is available for coupling reactions during peptide synthesis, while the N-methylation improves the overall peptide's pharmacokinetic properties, such as oral bioavailability and half-life.

Studying Structure-Activity Relationships:

Boc-N-Me-Leu-OH is also valuable in structure-activity relationship (SAR) studies, where researchers examine how small changes in peptide structure (such as introducing N-methylated amino acids) affect biological activity.
For example, modifying the leucine side chain by adding a methyl group can help researchers understand the role of side-chain modifications on peptide folding, target binding, and activity.

Peptide Libraries and Screening:

Boc-N-Me-Leu-OH can be incorporated into peptide libraries, where different N-methylated amino acids are used to explore their effects on peptide binding affinity, biological function, and structural integrity.
Researchers can screen these libraries to identify peptides with optimal stability and activity for specific biological targets, including receptors, enzymes, and antimicrobial agents.

Package

Transportation

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

Company Profile