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ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+
ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+

Large Image :  ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ Get Best Price

Product Details:
Place of Origin: CHINA
Brand Name: Enlai Biotech
Certification: ISO 9001 COA HPLC NMR
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Inside: double PE bag Outside: paper drum
Delivery Time: In Stock
Payment Terms: T/T
Supply Ability: 100 kilograms per month
Detailed Product Description
Product Name: Fmoc-Gly-Gly-Phe-OH CAS No: 160036-44-2
M.W: 501.53 Appearance: White Powder
Purity: 99+ Storage: Room Temperature

 

Product Description

 

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+

 

NameFmoc-Gly-Gly-Phe-OH

CAS NO: 160036-44-2

M.W: 501.53

Appearance: White Powder

Purity: 98+   

Synonyms: Fmoc-Gly-Gly-Phe-OH

 

Application

 

1. Cleavable Linker Design

Fmoc-Gly-Gly-Phe-OH contains a Gly-Gly-Phe (GGF) tripeptide sequence that can serve as a protease-sensitive linker in ADCs.

This type of sequence is recognized and cleaved by lysosomal enzymes such as Cathepsin B, which are highly expressed in tumor cells.

Upon internalization of the ADC by the target cancer cell, the GGF linker is cleaved, triggering the release of the cytotoxic payload.

 

2. Enhanced Tumor Selectivity and Drug Release

The use of enzyme-sensitive linkers like GGF ensures that the drug is released specifically within the tumor environment, limiting systemic toxicity.

It contributes to precise and controlled intracellular release of the active drug (e.g., MMAE, DM1).

 

Package

 

 ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 0     ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 1 

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 2ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 3

Transportation

 

Small package(1g, 25g, 1Kg, 25Kg) can be shipped by Express. (DHL, FedEx, EMS, etc.)
Large package(100kg and more than100Kg) can be transported by Air or Sea.

All transportation is in accordance with the customer's needs.

 

Company Profile

 

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 4ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 5

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 6ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 7

ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 8ADC Raw materials Fmoc-Gly-Gly-Phe-OH CAS NO. 160036-44-2 HPLC 99+ 9

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